NOT KNOWN FACTS ABOUT AHU'S

Around 80% of TTP is induced by deficient action of ADAMTS13. ADAMTS13 deficiency can be constitutive, because of biallelic ADAMTS13 pathogenic variants; or acquired, because of an inhibitory antibody. Evaluation of ADAMTS13 action is executed working with assessments based upon the potential on the protease to cleave conventional VWF multimers in